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Antiochus II Theos (286–246 bc). Succeeded Antiochus I Soter, his father, to the Seleucid throne (r. 261–246 bc). The Greeks of Miletus called him “Theos” (Θεός, Theos), meaning “the Divine” or “the God,” because he killed their tyrant Timarchus (Appian, Syriaca 65; compare Josephus, Antiquities 12.125). Antiochus II waged war with Ptolemy II Philadelphus, “the king of the south” (Dan 11:6–9). He made peace with Ptolemy in 250 bc and married Ptolemy’s daughter Berenice. Antiochus II, Berenice, and Berenice’s infant son were later assassinated by Antiochus’ first wife Laodice in 246 bc, so that Laodice’s son with Antiochus—Seleucus II Callinicus—would succeed to the throne (Appian, Syriaca 65–66).

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