Agnosticism There are various approaches or methods to the question of God, some positive and some negative. Perhaps the most widely held in the latter category is agnosticism. There are two basic kinds of agnostics: those who claim that the existence and nature of God are not known, and those who hold God to be unknowable. Since the first type does not eliminate all religious knowledge, attention here will center on the last one. The term agnosticism was coined by T. H. Huxley. It means literally