132 Here δέ (de) has been translated as “so” to indicate that Jesus’ pronouncement is a result of their statements about his disciples.
133 Grk “the sons of the wedding hall,” an idiom referring to guests at the wedding, or more specifically, friends of the bridegroom present at the wedding celebration (L&N 11.7).
134 The expression while the bridegroom is with them is an allusion to messianic times (John 3:29; Isa 54:5–6; 62:4–5; 4 Ezra 2:15, 38).
135 Questions prefaced with μή (mē) in Greek anticipate a negative answer. This can sometimes be indicated by using a “tag” at the end in English (here it is “can you?”).

In other versions

And Jesus said to them, “Can you make wedding guests fast while the bridegroom is with them?

Jesus answered, “Can you make the friends of the bridegroom fast while he is with them?

Jesus said to them, “You can’t make the wedding guests fast while the groom is with them, can you?

Jesus responded, “Do wedding guests fast while celebrating with the groom? Of course not.

So he said to them, “You are not able to make the bridegroom’s attendants fast as long as the bridegroom is with them, are you?

And he said unto them, Can ye make the children of the bridechamber fast, while the bridegroom is with them?

Public Domain