45 The construction uses a perfect verbal form with the vav consecutive to introduce the conditional clause and then another perfect verbal form with a vav consecutive to complete the sentence: “if you take … then you will bring down.”
46 The expression bring down my gray hair is figurative, using a part for the whole—they would put Jacob in the grave. But the gray head signifies a long life of worry and trouble. See Gen 42:38.
47 Heb “evil/calamity.” The term is different than the one used in the otherwise identical statement recorded in v. 31 (see also 42:38).
48 Heb “to Sheol,” the dwelling place of the dead.

In other versions

If you take this one also from me, and harm happens to him, you will bring down my gray hairs in evil to Sheol.’

If you take this one from me too and harm comes to him, you will bring my gray head down to the grave in misery.’

If you also take this one from me and anything happens to him, you will bring my gray hairs down to Sheol in sorrow.’

Now if you take his brother away from me, and any harm comes to him, you will send this grieving, white-haired man to his grave.’

And if you take this one also from me, and he encounters harm, you will bring down my gray head in sorrow to Sheol.’

And if ye take this also from me, and mischief befall him, ye shall bring down my gray hairs with sorrow to the grave.

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