21 Heb “she lifted up her eyes toward,” an expression that emphasizes her deliberate and careful scrutiny of him.
22 Heb “lie with me.” Here the expression “lie with” is a euphemism for sexual intercourse. The story of Joseph and Potiphar’s wife has long been connected with the wisdom warnings about the strange woman who tries to seduce the young man with her boldness and directness (see Prov 5–7, especially 7:6–27). This is part of the literary background of the story of Joseph that gives it a wisdom flavor. See G. von Rad, God at Work in Israel, 19–35; and G. W. Coats, “The Joseph Story and Ancient Wisdom: A Reappraisal,” 35 (1973): 285–97.

In other versions

And after a time his master’s wife cast her eyes on Joseph and said, “Lie with me.”

and after a while his master’s wife took notice of Joseph and said, “Come to bed with me!”

After some time his master’s wife looked longingly at Joseph and said, “Sleep with me.”

and Potiphar’s wife soon began to look at him lustfully. “Come and sleep with me,” she demanded.

And it happened that after these things his master’s wife cast her eyes on Joseph, and she said, “Lie with me.”

And it came to pass after these things, that his master’s wife cast her eyes upon Joseph; and she said, Lie with me.

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