Ephraim and Manasseh are born
Joseph and Asenath had two sons named Ephraim and Manasseh during the years before the famine.
Key passages
Ge 41:50–52

Before the year of famine came, two sons were born to Joseph, whom Asenath, daughter of Potiphera priest of On, bore to him. And Joseph called the name of the firstborn Manasseh, for he said, “God has caused me to forget all my hardship and all my father’s house.” And the name of the second …

See also
Ge 46:20; Ge 48:5;